The 2025 Major League Baseball regular season will begin at the Tokyo Dome on March 18, when the Chicago Cubs take on the Los Angeles Dodgers at 6 a.m. EDT on FOX. The second game of the MLB World Tour Tokyo Series will follow on March 19 at 6 a.m. EDT on Fox Sports 1.
The Tokyo Series will also be broadcast in Spanish on FOX Deportes for both games. The Cubs will serve as the home team for both matchups.
According to MLB researcher Sarah Langs, Dodgers starting pitcher Yoshinobu Yamamoto will start Game 1 of the 2025 regular season, while the Cubs have named left-hander Shota Imanaga as their starter for the March 18 opener at the Tokyo Dome.
Yoshinobu Yamamoto vs Shota Imanaga in Game 1 in Japan will be:
– the first matchup of Japanese-born SP in a regular-season MLB game at the Tokyo Dome
-the first matchup between Japanese-born SP in an Opening Day game https://t.co/PKLtLG2Eu2
— Sarah Langs (@SlangsOnSports) February 18, 2025
The Dodgers and Cubs will play the first game of spring training for the 2025 Cactus League season on Thursday, February 20, at 3:05 p.m. EST at Camelback Ranch in Glendale, Ariz. This will be the only game played that day, as the remaining 28 teams will begin their exhibition schedules between February 21 and March 25.
As part of their MLB World Tour Tokyo Series preparations, the Dodgers will face two Nippon Professional Baseball (NPB) franchises at the Tokyo Dome. They will play the Yomiuri Giants on March 15 at 6 a.m. EDT and the Hanshin Tigers later that day at 11 p.m. EDT.
The Cubs will also participate in NPB exhibition games, taking on the Hanshin Tigers on March 14 at 11 p.m. EDT and the Yomiuri Giants on March 16 at 6 a.m. EDT, both at the Tokyo Dome.
Major League Baseball has hosted regular-season games at the Tokyo Dome six times in 2000, 2004, 2008, 2012, and 2019, prior to the 2025 season.
The Cubs were the first MLB team to play in Japan, facing the New York Mets at the Tokyo Dome on March 29-30, 2000. The New York Yankees followed in 2004, taking on the Tampa Bay Devil Rays on March 30-31. The Boston Red Sox played the Oakland Athletics in 2008 on March 25-26. The Athletics faced the Seattle Mariners on March 28-29, 2012, and again in 2019, when they played the Mariners on March 20-21.
The MLB Japan All-Star Series took place after every season from 1986 to 2006, with games played across several Japanese stadiums. The series was held at Korakuen Stadium, Osaka Stadium, Lions Stadium, and Heiwadai Stadium in 1986. It moved to the Tokyo Dome, Koshien Stadium, Seibu Lions Stadium, and Heiwadai Stadium in 1988. In 1990, the games were held at Chiba Marine Stadium, Seibu Lions Stadium, Heiwadai Stadium, and the Tokyo Dome. The 1992 series featured matchups at Koshien Stadium, Chiba Marine Stadium, and the Tokyo Dome. In 1996, games were played at Yokohama Stadium, Seibu Lions Stadium, Koshien Stadium, and the Tokyo Dome. The 1998 series was held entirely at the Tokyo Dome. In 2000, the games were split between the Tokyo Dome and Nagoya Dome. The 2002 series was hosted at the Osaka Dome, the Sapporo Dome, the Fukuoka Dome, and the Tokyo Dome. In 2004, the locations were the Osaka Dome, the Fukuoka Dome, the Nagoya Dome, and the Tokyo Dome. The 2006 series was played at the Tokyo Dome, Osaka Dome, and Fukuoka Dome.
The 1994 MLB Japan All-Star Series was canceled due to the MLB Players’ Strike, which ended the regular season on August 11, 1994. The dispute arose from collective bargaining issues between the MLB Players Association and MLB franchise owners over pro-rated salary pay and other financial terms.
From 1986 to 2006, the MLB All-Stars held a dominant record of 48 wins, 20 losses, and 7 ties against the NPB All-Stars. The MLB All-Stars had ten MVP Award winners over the NPB All-Stars. Tony Pena won in 1986, Barry Larkin in 1988, Ken Griffey Jr. in 1990, Mark Grace in 1992, Steve Finley in 1996, Sammy Sosa in 1998, Barry Bonds in 2000, Torii Hunter in 2002, Vernon Wells in 2004, and Ryan Howard in 2006. The NPB All-Stars never had an MVP winner in any of the matchups against the MLB All-Stars.

